Neuropeptides
Volume 44, Issue 5 , Pages 413-420 , October 2010

Effects of acute ethanol administration on methionine–enkephalin expression and release in regions of the rat brain

  • M. Méndez

      Affiliations

    • Departamento de Neuroquímica, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente, Calzada México Xochimilco 101, Col. San Lorenzo Huipulco, 14370 México D.F., Mexico
    • Corresponding Author InformationCorresponding author. Tel.: +52 55 41 60 50 91; fax: +52 55 55 13 37 22.
  • ,
  • I.G. Barbosa-Luna

      Affiliations

    • Departamento de Neuroquímica, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente, Calzada México Xochimilco 101, Col. San Lorenzo Huipulco, 14370 México D.F., Mexico
  • ,
  • J.M. Pérez-Luna

      Affiliations

    • Departamento de Neuroquímica, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente, Calzada México Xochimilco 101, Col. San Lorenzo Huipulco, 14370 México D.F., Mexico
  • ,
  • A. Cupo

      Affiliations

    • Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique (CNRS), Université de Nice-Sophia-Antipolis, 660 Route des Lucioles, 06560 Valbonne, France
  • ,
  • J. Oikawa

      Affiliations

    • Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados, Calzada de los Tenorios 235, Col. Granjas-Coapa, 14330 México D.F., Mexico

Received 11 December 2009 ,Accepted 8 May 2010.

References 

  1. Bach FW, Yaksh TL. Release into ventriculo-cisternal perfusate of beta-endorphin- and Met-enkephalin-immunoreactivity: effects of electrical stimulation in the arcuate nucleus and periaqueductal gray of the rat. Brain Res. 1995;690:167–176
  2. Banks WA, Wolf KM, Niehoff ML. Effects of chronic ethanol on brain and serum level of methionine enkephalin. Peptides. 2003;24:1935–1940
  3. Camacho A, Montiel T, Massieu L. The annion channel blocker, 4,4′-dinitrostilbene-2,2′-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo. Neuroscience. 2006;142:1005–1017
  4. Cupo A, Jarry T. Detection of methionine–enkephalin at the 10−16mole level. J. Neuroimmunol. 1985;8:57–67
  5. Daugé V, Mauborgne A, Cesselin F, Fournié-Zaluski M-C, Roques B-P. The dual peptidase inhibitor RB101 induces a long-lasting increase in the extracellular level of Met-enkephalin-like material in the nucleus accumbens of freely moving rats. J. Neurochem. 1996;67:1301–1308
  6. Di Chiara G, Acquas E, Tanda G. Ethanol as a neurochemical surrogate of conventional reinforcers: the dopamine-opioid link. Alcohol. 1996;13:13–17
  7. Di Chiara G, Imperato A. Ethanol preferentially stimulates dopamine release in the nucleus accumbens of freely moving rats. Eur. J. Pharmacol. 1985;115:131–132
  8. Diniz PH, Silva JH, Gomez MV, Guatimosim C, Gomez RS. Halothane increases non-vesicular [(3)H]dopamine release from brain cortical slices. Cell. Mol. Neurobiol. 2007;27:757–770
  9. Fadda F, Argiolas A, Melis MR, Serra G, Gessa GL. Differential effects of acute and chronic ethanol on dopamine metabolism in frontal cortex, caudate nucleus and substantia nigra. Life Sci. 1980;27:979–986
  10. Froehlich JC. Genetic factors in alcohol self-administration. J. Clin. Psychiatry. 1995;56(Suppl. 7):15–23
  11. Froehlich JC, Zweifel M, Harts J, Lumeng L, Li T-K. Importance of delta opioid receptors in maintaining high alcohol drinking. Psychopharmacology. 1991;103:467–472
  12. Gessa GL, Muntoni F, Collu M, Vargiu L, Mereu G. Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res. 1985;348:201–203
  13. Gianoulakis C, Krishnan B, Thavundayil J. Enhanced sensitivity of pituitary beta-endorphin to ethanol in subjects at high risk of alcoholism. Arch. Gen. Psychiatry. 1996;53:250–257
  14. Gingras MA, Cools AR. Analysis of the biphasic locomotor response to ethanol in high and low responders to novelty: a study in Nijmegen Wistar rats. Psychopharmacology. 1996;125:258–264
  15. Gobaille S, Schmidt C, Cupo A, Herbrecht F, Maitre M. Characterization of methionine–enkephalin release in the rat striatum by in vivo dialysis: effects of gamma-hydroxybutyrate on cellular and extracellular methionine–enkephalin levels. Neuroscience. 1994;60:637–648
  16. Hernández-Vázquez F, Méndez M. Stimulant and depressant behavioral actions of alcohol in non-selected Wistar rats. In:  Chen FJ editors. New Trends in Brain Research. New York: Nova Science Publishers, Inc.; 2006;p. 127–142
  17. Herz A. Endogenous opioid systems and alcohol addiction. Psychopharmacology (Berl). 1997;12:99–111
  18. Honkanen A, Vilamo L, Wegelius K, Sarviharju M, Hyytiä P, Korpi ER. Alcohol drinking is reduced by a μ1- but not by a δ-opioid receptor antagonist in alcohol-preferring rats. Eur. J. Pharmacol. 1996;304:7–13
  19. Hyytiä P, Kiianmaa K. Suppression of ethanol responding by centrally administered CTOP and naltrindole in AA and Wistar rats. Alcohol. Clin. Exp. Res. 2001;25:25–33
  20. Jarjour S, Bai L, Gianoulakis C. Effect of acute ethanol administration on the release of opioid peptides from the midbrain including the ventral tegmental area. Alcohol. Clin. Exp. Res. 2009;33:1033–1043
  21. Joyce EM, Iversen SD. The effect of morphine applied locally to mesencephalic dopamine cell bodies on spontaneous motor activity in the rat. Neurosci. Lett. 1979;14:207–212
  22. Kalivas PW, Widerläv E, Stanley D, Breese G, Prange AJ. Enkephalin action on the mesolimbic system: a dopamine-dependent and a dopamine-independent increase in locomotor activity. J. Pharmacol. Exp. Ther. 1983;227:229–237
  23. Koob GF. Neural mechanisms of drug reinforcement. Ann. NY Acad. Sci. 1992;654:171–191
  24. Koob GF, Sanna PP, Bloom FE. Neuroscience of addiction. Neuron. 1998;21:467–476
  25. Krishnan-Sarin S, Jing SL, Kurtz DL, Zweifel M, Portoghese PS, Li T-K, et al. The delta opioid receptor antagonist naltrindole attenuates both alcohol and saccharin intake in rats selectively bred for alcohol preference. Psychopharmacology. 1995;120:177–185
  26. Krishnan-Sarin S, Portoghese PS, Li T-K, Froehlich JC. The delta2-opioid receptor antagonist naltriben selectively attenuates alcohol intake in rats bred for alcohol preference. Pharmacol. Biochem. Behav. 1995;52:153–159
  27. Krishnan-Sarin S, Wand GS, Li X-W, Li T-K, Portoghese PS, Froehlich JC. Effect of mu opioid receptor blockade on alcohol intake in rats bred for high alcohol drinking. Pharmacol. Biochem. Behav. 1998;59:627–635
  28. Lam MP, Marinelli PW, Bai L, Gianoulakis C. Effects of acute ethanol on opioid peptide release in the central amygdala: an in vivo microdialysis study. Psychopharmacology. 2008;201:261–271
  29. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the folin phenol reagent. J. Biol. Chem. 1951;193:265–275
  30. Luna SP, Taylor PM. Pituitary–adrenal activity and opioid release in ponies during thiopentone/halothane anaesthesia. Res. Vet. Sci. 1995;58:35–41
  31. Marinelli PW, Bai L, Quirion R, Gianoulakis C. A microdialysis profile of Met-enkephalin release in the rat nucleus accumbens following alcohol administration. Alcohol. Clin. Exp. Res. 2005;29:1821–1828
  32. Méndez M, Leriche M, Calva JC. Acute ethanol administration differentially modulates μ opioid receptors in the rat meso-accumbens and mesocortical pathways. Mol. Brain Res. 2001;94:148–156
  33. Méndez M, Morales-Mulia M. Ethanol exposure differentially alters pro-enkephalin mRNA expression in regions of the mesocorticolimbic system. Psychopharmacology. 2006;189:117–124
  34. Méndez M, Morales-Mulia M. Role of mu and delta opioid receptors in alcohol drinking behaviour. Curr. Drug Abuse Rev. 2008;1:239–252
  35. Méndez M, Morales-Mulia M. Ethanol exposure and Pro-enkephalin mRNA expression in regions of the mesocorticolimbic system. In:  Sher L editors. Research on the Neurobiology of Alcohol Use Disorders. New York: Nova Science Publishers, Inc.; 2008;p. 177–202
  36. Méndez M, Morales-Mulia M, Leriche M. [3H]DPDPE binding to opioid receptors in the rat mesocorticolimbic and nigrostriatal pathways is transiently increased by acute ethanol administration. Brain Res. 2004;1028:180–190
  37. Méndez M, Morales-Mulia M, Pérez-Luna JM. Ethanol-induced changes in Proenkephalin mRNA expression in the rat nigrostriatal pathway. J. Mol. Neurosci. 2008;34:225–234
  38. Myers RD, Borg S, Mossberg R. Antagonism by naltrexone of voluntary alcohol selection in the chronically drinking macaque monkey. Alcohol. 1986;3:383–388
  39. Nylander I, Hyytiä P, Forsander O, Terenius L. Differences between alcohol-preferring (AA) and alcohol-avoiding (ANA) rats in the prodynorphin and proenkephalin systems. Alcohol. Clin. Exp. Res. 1994;18:1272–1279
  40. O’Malley S, Jaffe AJ, Chang G, Schottenfeld RS, Meyer RE, Rounsaville B. Naltrexone and coping skills therapy for alcohol dependence. Arch. Gen. Psychiatry. 1992;49:881–887
  41. Pashkov VN, Hemmings HC. The effects of general anesthetics on norepinephrine release from isolated rat cortical nerve terminals. Anesth. Analg. 2002;95:1274–1281
  42. Pashkov VN, Westphalen RI, Hemmings HC. General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals. Anesthesiology. 2002;97:1500–1506
  43. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. forth ed.. San Diego: Academic Press; 1998;
  44. Ploj K, Roman E, Gustavsson L, Nylander I. Basal levels and alcohol-induced changes in nociceptin/orphanin FQ, dynorphin, and enkephalin levels in C57BL/6J mice. Brain Res. Bull. 2000;53:219–226
  45. Ploj K, Roman E, Kask A, Hyytiä P, Schiöth HB, Wikberg JES, et al. Effects of melanocortin receptor ligands on ethanol intake and opioid peptide levels in alcohol-preferring AA rats. Brain Res. Bull. 2002;59:97–104
  46. Rasmussen DD, Bryant CA, Boldt BM, Colasurdo EA, Levin N, Wilkinson CW. Acute alcohol effects on opiomelanocortinergic regulation. Alcohol. Clin. Exp. Res. 1998;22:789–801
  47. Reid LD, Hunter GA. Morphine and naloxone modulate intake of ethanol. Alcohol. 1984;1:33–37
  48. Roberts AJ, Gold LH, Polis I, McDonald JS, Filliol D, Kieffer BL, et al. Increased ethanol self-administration in delta-opioid receptor knockout mice. Alcohol. Clin. Exp. Res. 2001;25:1249–1256
  49. Roberts AJ, McDonald JS, Heyser CJ, Kieffer BL, Matthes HWD, Koob GF, et al. μ-opioid receptor knockout mice do not self-administer alcohol. J. Pharmacol. Exp. Ther. 2000;293:1002–1008
  50. Schulz R, Wüster M, Duka T, Herz A. Acute and chronic ethanol treatment changes endorphin levels in brain and pituitary. Psychopharmacology. 1980;68:221–227
  51. Seizinger BR, Bovermann K, Maysinger D, Holt V, Herz A. Differential effects of acute and chronic ethanol treatment on particular opioid systems in discrete regions of rat brain and pituitary. Pharmacol. Biochem. Behav. 1983;18:361–369
  52. Silva JH, Gomez MV, Silva JH, Guatimosim C, Gomez RS. Halothane induces vesicular and carrier-mediated release of [3H]serotonin from rat brain cortical slices. Neurochem. Int. 2008;52:1240–1246
  53. Stromberg MF, Casale M, Volpicelli L, Volpicelli JR, O’Brien CP. A comparison of the effects of the opioid antagonists naltrexone, naltrindole, and β-funaltrexamine on ethanol consumption in the rat. Alcohol. 1998;15:281–289
  54. Ulm RR, Volpicelli JR, Volpicelli LA. Opiates and alcohol self-administration in animals. J. Clin. Psychiatry. 1995;56(Suppl. 7):5–14
  55. Volpicelli JR, Ulm RR, Hopson N. Alcohol drinking in rats during and following morphine injections. Alcohol. 1991;8:289–292
  56. Westphalen RI, Hemmings HC. Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release. J. Pharmacol. Exp. Ther. 2006;316:208–215
  57. Westphalen RI, Hemmings HC. Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release. J. Pharmacol. Exp. Ther. 2006;316:216–223
  58. Wild, K.D., Reid, L.D., 1990. Modulation of ethanol intake by morphine: evidence for a central site of action. Life Sci. 47, PL49–PL54.
  59. Wise RA, Bozarth MA. Action of drugs of abuse on brain reward systems: an update with specific attention to opiates. Pharmacol. Biochem. Behav. 1982;17:239–243
  60. Yim HJ, Robinson DL, White ML, Jaworski JN, Randall PK, Lancaster FE, et al. Dissociation between the time course of ethanol and extracellular dopamine concentrations in the nucleus accumbens after a single intraperitoneal injection. Alcohol. Clin. Exp. Res. 2000;24:781–788

PII: S0143-4179(10)00050-8

doi: 10.1016/j.npep.2010.05.001

Neuropeptides
Volume 44, Issue 5 , Pages 413-420 , October 2010