« Previous
Next »
Neuropeptides
Volume 44, Issue 3
, Pages 261-268
, June 2010
Y4 receptors and pancreatic polypeptide regulate food intake via hypothalamic orexin and brain-derived neurotropic factor dependent pathways
References
- . Mechanisms of neuropeptide Y, peptide YY, and pancreatic polypeptide inhibition of identified green fluorescent protein-expressing GABA neurons in the hypothalamic neuroendocrine arcuate nucleus. J. Neurosci. 2005;25:7406–7419
- Distribution and release of human pancreatic polypeptide. Gut. 1976;17:940–944
- Urocortin reduces food intake and gastric emptying in lean and ob/ob obese mice. Gastroenterology. 1999;116:1287–1292
- Characterization of the effects of pancreatic polypeptide in the regulation of energy balance. Gastroenterology. 2003;124:1325–1336
- Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY(32–36): development of an anorectic Y4 receptor selective agonist with picomolar affinity. J. Med. Chem. 2006;49:2661–2665
- Pancreatic polypeptide reduces appetite and food intake in humans. J. Clin. Endocrinol. Metab. 2003;88:3989–3992
- . Metabolic and neuroendocrine indices one month after lateral hypothalamic area lesions. Physiol. Behav. 1992;52:133–139
- Orexin neurons express a functional pancreatic polypeptide Y4 receptor. J. Neurosci. 2003;23:1487–1497
- Acute effects of PYY3-36 on food intake and hypothalamic neuropeptide expression in the mouse. Biochem. Biophys. Res. Commun. 2003;311:915–919
- Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature. 2001;411:480–484
- . GABA: a dominant neurotransmitter in the hypothalamus. J. Comput. Neurol. 1990;302:1019–1037
- . Hypocretin/orexin: a molecular link between sleep, energy regulation, and pleasure. J. Neuropsychiatry Clin. Neurosci. 2007;19:413–419
- Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat. Peptides. 1999;20:1099–1105
- . GABAergic and catecholaminergic innervation of mediobasal hypothalamic beta-endorphin cells projecting to the medial preoptic area. Neuroscience. 1992;51:391–399
- . Regulation of alpha-melanocyte-stimulating hormone release from hypothalamic neurons. Ann. NY Acad. Sci. 1993;680:260–278
- Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1. Nat. Med. 2007;13:1333–1340
- . The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol. Behav. 2006;87:221–244
- Subcellular localization of glucose transporter 4 in the hypothalamic arcuate nucleus of ob/ob mice under basal conditions. Brain Res. 2005;1049:34–42
- . Induction of brain-derived neurotrophic factor by leptin in the ventromedial hypothalamus. Neuroscience. 2006;139:1107–1115
- . Critical role of arcuate Y4 receptors and the melanocortin system in pancreatic polypeptide-induced reduction in food intake in mice. PLOS One. 2009;4:e8488
- . Effect of pancreatic polypeptide on rat dorsal vagal complex neurons. J. Physiol. 1997;499:475–483
- . Localization of Y-receptor subtype mRNAs in rat brain by digoxigenin labeled in situ hybridization. Neuropeptide Y Protocols. 2000;153:165–183
- . Orexins and appetite regulation. Neuropeptides. 2002;36:303–325
- Y4 receptor knockout rescues fertility in ob/ob mice. Genes Develop. 2002;16:1077–1088
- . Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice. Diabetes. 2002;51:3420–3427
- . Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 1998;92(4):573–585
- Acute effects of brain-derived neurotrophic factor on energy expenditure in obese diabetic mice. Int. J. Obes. Relat. Metab. Disord. 2001;25:1286–1293
- Decreased food intake and body weight in pancreatic polypeptide-overexpressing mice. Gastroenterology. 1999;117:1427–1432
- . Role of melanocortins in the central control of feeding. Eur. J. Pharmacol. 2000;405:25–32
- Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat. Neurosci. 2003;6:736–742
PII: S0143-4179(10)00005-3
doi: 10.1016/j.npep.2010.01.001
© 2010 Elsevier Ltd. All rights reserved.
« Previous
Next »
Neuropeptides
Volume 44, Issue 3
, Pages 261-268
, June 2010
