Neuropeptides
Volume 44, Issue 2 , Pages 163-168 , April 2010

Role of kinin B1 and B2 receptors in memory consolidation during the aging process of mice

  • Mayra Tolentino Resk Lemos

      Affiliations

    • Department of Physiological Sciences, Faculdade de Ciências Médicas da Santa Casa de São Paulo. Rua Dr. Cesario Motta Junior, 61, São Paulo, SP, CEP 01221-020, Brazil
    • ,
  • Fabio Agostini Amaral

      Affiliations

    • Department of Physiological Sciences, Faculdade de Ciências Médicas da Santa Casa de São Paulo. Rua Dr. Cesario Motta Junior, 61, São Paulo, SP, CEP 01221-020, Brazil
    • ,
  • Karis Ester Dong

      Affiliations

    • Department of Physiological Sciences, Faculdade de Ciências Médicas da Santa Casa de São Paulo. Rua Dr. Cesario Motta Junior, 61, São Paulo, SP, CEP 01221-020, Brazil
    • ,
  • Maria Fernanda Queiroz Prado Bittencourt

      Affiliations

    • Department of Physiological Sciences, Faculdade de Ciências Médicas da Santa Casa de São Paulo. Rua Dr. Cesario Motta Junior, 61, São Paulo, SP, CEP 01221-020, Brazil
    • ,
  • Ariadiny Lima Caetano

      Affiliations

    • Department of Physiological Sciences, Faculdade de Ciências Médicas da Santa Casa de São Paulo. Rua Dr. Cesario Motta Junior, 61, São Paulo, SP, CEP 01221-020, Brazil
    • ,
  • João Bosco Pesquero

      Affiliations

    • Department of Biophysics, Universidade Federal de São Paulo. Rua Botucatu, 862, 7° andar, São Paulo, SP, CEP 04023-900l, Brazil
    • ,
  • Tania Araujo Viel

      Affiliations

    • School of Arts, Sciences and Humanities, Universidade de São Paulo, Rua Arlindo Bettio, 1000, São Paulo, SP, CEP 03828-000, Brazil
    • ,
  • Hudson Sousa Buck

      Affiliations

    • Department of Physiological Sciences, Faculdade de Ciências Médicas da Santa Casa de São Paulo. Rua Dr. Cesario Motta Junior, 61, São Paulo, SP, CEP 01221-020, Brazil
    • Corresponding Author InformationCorresponding author. Tel./fax: +55 11 3331 2008.

References 

  1. Amaral FA, Lemos MTR, Dong KE, Bittencourt MFQP, Caetano AL, Pesquero JB, et al. Participation of kinin receptors on memory impairment after chronic infusion of human amyloid-β 1-40 (A β) peptide in mice. Neuropeptides. 2010;44(2):93–97
  2. Bhoola KD, Figueroa CD, Worthy K. Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol. Rev. 1992;44(1):1–80
  3. Boix F, Rosenborg L, Hilgenfeldt U, Knardahl S. Contraction-related factors affect the concentration of a kallidin-like peptide in rat muscle tissue. J. Physiol. 2002;544(Pt 1):127–136
  4. Bovenzi V, Savard M, Morin J, Cuerrier CM, Grandbois M, Gobeil FJr. Bradykinin protects against brain microvascular endothelial cell death induced by pathophysiological stimuli. J. Cell. Physiol. 2010;222(1):168–176
  5. Buck HS, Ongali B, Thibault G, Lindsey CJ, Couture R. Autoradiographic detection of kinin receptors in the human medulla of control, hypertensive, and diabetic donors. Can. J. Physiol. Pharmacol. 2002;80(4):249–257
  6. Cloutier F, Ongali B, Campos MM, Thibault G, Neugebauer W, Couture R. Correlation between brain bradykinin receptor binding sites and cardiovascular function in young and adult spontaneously hypertensive rats. Br. J. Pharmacol. 2004;142(2):285–296
  7. Conde JR, Streit WJ. Microglia in the aging brain. J. Neuropathol. Exp. Neurol. 2006;65(3):199–203
  8. Couture R, Lindsey CJ. Brain kallikrein–kinin system: from receptors to neuronal pathways and physiological functions. In:  Quirion R, Björklund ,  Hökfelt T editor. Handbook of Chemical Neuroanatomy. vol. 16:Elsevier Science B.V.; 2000;p. 241–300
  9. Erdös E, Skidgel R. Metabolism of bradykinin by peptidases in health and disease. In:  Farmer S editors. The kinin system. San Diego: Academic Press; 1997;p. 111–141
  10. Hein AM, O’Banion MK. Neuroinflammation and memory: the role of prostaglandins. Mol. Neurobiol. 2009;40(1):15–32
  11. Iores-Marçal LM, Viel TA, Buck HS, Nunes VA, Gozzo AJ, Cruz-Silva I, et al. Bradykinin release and inactivation in brain of rats submitted to an experimental model of Alzheimer’s disease. Peptides. 2006;27(12):3363–3369
  12. Jenkins DW, Sellers LA, Feniuk W, Humphrey PP. Characterization of bradykinin-induced prostaglandin E2 release from cultured rat trigeminal ganglion neurones. Eur. J. Pharmacol. 2003;469(1–3):29–36
  13. Kozlowski MR, Rosser MP, Hall E. Identification of 3Hbradykinin binding sites in PC-12 cells and brain. Neuropeptides. 1988;12:207–211
  14. Langberg H, Bjørn C, Boushel R, Hellsten Y, Kjaer M. Exercise-induced increase in interstitial bradykinin and adenosine concentrations in skeletal muscle and peritendinous tissue in humans. J. Physiol. 2002;542(Pt 3):977–983
  15. Leeb-Lundberg LMF, Marceau F, Müller-Esterl W, Pettibone DJ, Zuraw BL. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol. Rev. 2005;57:27–77
  16. Lim SK, Park MJ, Jung HK, Park AY, Kim DI, Kim JC, et al. Bradykinin stimulates glutamate uptake via both B1R and B2R activation in a human retinal pigment epithelial cells. Life Sci. 2008;83(23–24):761–770
  17. Marceau F, Larrivée JF, Saint-Jacques E, Bachvarov DR. The kinin B1 receptor: an inducible G protein coupled receptor. Can. J. Physiol. Pharmacol. 1997;75(6):725–730
  18. Mayhan WG. Regulation of blood–brain barrier permeability. Microcirculation. 2001;8(2):89–104
  19. McGaugh JL. Involvement of hormonal and neuromodulatory systems in the regulation of memory storage. Annu. Rev. Neurosci. 1989;12:255–287
  20. McGeer EG, McGeer PL. Inflammatory processes in Alzheimer’s disease. Prog. Neuropsychopharmacol. Biol. Psychiatry. 2003;27:741–749
  21. Medina JH, Bekinschtein P, Cammarota M, Izquierdo I. Do memories consolidate to persist or do they persist to consolidate?. Behav. Brain Res. 2008;192(1):61–69
  22. Miller KR, Streit WJ. The effects of aging, injury and disease on microglial function: a case for cellular senescence. Neuron Glia Biol. 2007;3:245–253
  23. Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Methods. 1984;11:47–60
  24. Noda M, Sasaki K, Ifuku M, Wada K. Multifunctional effects of bradykinin on glial cells in relation to potential anti-inflammatory effects. Neurochem. Int. 2007;51:185–191
  25. Noda M, Kariura Y, Pannasch U, Nishikawa K, Wang L, Seike T, et al. Neuroprotective role of bradykinin because of the attenuation of proinflammatory cytokine release from activated microglia. J. Neurochem. 2007;101:397–410
  26. Prat A, Biernacki K, Pouly S, Nalbantoglu J, Couture R, Antel JP. Kinin B1 receptor expression and function on human brain endothelial cells. J. Neuropathol. Exp. Neurol. 2000;59:896–906
  27. Prat A, Weinrib L, Becher B, Poirier J, Duquette P, Couture R, et al. Bradykinin B1 receptor expression and function on T lymphocytes in active multiple sclerosis. Neurology. 1999;53:2087–2092
  28. Prediger RD, Medeiros R, Pandolfo P, Duarte FS, Passos GF, Pesquero JB, et al. Genetic deletion or antagonism of kinin B(1) and B(2) receptors improves cognitive deficits in a mouse model of Alzheimer’s disease. Neuroscience. 2008;151(3):631–643
  29. Quillfeldt JA, Zanatta MS, Schmitz PK, Quevedo J, Schaeffer E, Lima JB, et al. Different brain areas are involved in memory expression at different times from training. Neurobiol. Learn. Mem. 1996;66(2):97–101
  30. Raidoo DM, Bhoola KD. Pathophysiology of the Kalikrein–Kinin system in mammalian nervous tissue. Pharmacol. Ther. 1998;79(2):105–127
  31. Raidoo DM, Bhoola KD. Kinin receptors on human neurons. J. Neuroimmunol. 1997;77:39–44
  32. Regoli D, Barabé J. Pharmacology of bradykinin and related kinins. Pharmacol. Rev. 1980;32(1):1–46
  33. Salminen A, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. Inflammation in Alzheimer’s disease: Amyloid-b oligomers trigger innate immunity defense via pattern recognition receptors. Prog. Neurobiol. 2009;87:181–194
  34. Shirotani K, Tsubuki S, Iwata N, Takaki Y, Harigaya W, Maruyama K, et al. Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan-and phosphoramidon-sensitive endopeptidases. J. Biol. Chem. 2001;276(24):21895–21901
  35. Steranka LR, Manning DC, DeHaas CJ, Ferkany JW, Borosky SA, Connor JR, et al. Bradykinin as a pain mediator: Receptors are localized to sensory neurons, and antagonists have analgesic actions. Proc. Natl. Acad. Sci. 1988;85:3245–3249
  36. Turner AJ, Fisk L, Nalivaeva NN. Targeting amyloid-degrading enzymes as therapeutic strategies in neurodegeneration. Ann. N. Y. Acad. Sci. 2004;1035:1–20
  37. Viel TA, Caetano AL, Nasello AG, Lancelotti CL, Nunes VA, Araujo MS, et al. Increases of kinin B(1) and B(2) receptors binding sites after brain infusion of amyloid-beta 1–40 peptide in rats. Neurobiol. Aging. 2008;29:1805–1814
  38. Walther T, Albrecht D, Becker M, Schubert M, Kouznetsova E, Wiesner B, et al. Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase. PLoS One. 2009;4(2):e4590
  39. Wang Q, Wang J. Injection of bradykinin or cyclosporine A to hippocampus induces Alzheimer-like phosphorylation of Tau and abnormal behavior in rats. Chin. Med. J. 2002;115(6):884–887
  40. Yasuyoshi H, Kashii S, Zhang S, Nishida A, Yamauchi T, Honda Y, et al. Protective effect of bradykinin against glutamate neurotoxicity in cultured rat retinal neurons. Invest. Ophthalmol. Vis. Sci. 2000;41(8):2273–2278

PII: S0143-4179(09)00145-0

doi: 10.1016/j.npep.2009.12.006

Neuropeptides
Volume 44, Issue 2 , Pages 163-168 , April 2010

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